Cultivated land function index and function advantage index were collected to analyze the spatiotemporal variation trend of cultivated land multi-functions and to find out zoning optimization strategies in Wuling Mountain Area of Hunan Province. The results were as follows: the temporal changes of cultivated land multi-functions were different and they all showed growth trends. The change rates of cultural, production, ecological security and social security functions decreased successively. It had obvious spatial heterogeneity for the cultivated land functions. The total function had changed from higher in the east and lower in the west, higher in the north and lower in the south in 2010 to four higher centers in 2020. The production function had changed from lower in the north and higher in the south to the higher centers concentrated in the east. The social security function had changed from higher in the east and lower in the west to higher centers local protrusions and medium areas widespread distribution. The ecological security function had changed from lower in the center and higher in the peripher to highest and higher areas distributed throughout the region. The research area could be divided into five types, namely that production-living, ecological-cultural, production, cultural, and living-ecological functions advantage areas.