A pot experiment was carried out to study the effects of two ecotypes(farmland and mine) of Solanum photeinocarpum post-grafting generation on the growth and cadmium(Cd) content of Ziziphus acidojujuba seedlings under Cd contaminated condition(5 mg/kg). The results showed that compared to single cropping intercropping decreased the biomass, plant height, soluble protein content and antioxidant enzyme activity of Z. acidojujuba seedlings. Under intercropping with self-anvilgeneration of farmland ecotype S. photeinocarpum, the decrease of biomass of Z. acidojujuba seedlings was the least and root biomass decreased by 25.51%; the decrease of soluble protein content and antioxidant enzyme activity of Z. acidojujuba seedlings was the biggest: soluble protein content decreased by 20.65%, SOD activity decreased by 20.59%, POD activity decreased by 35.91% and CAT activity decreased by 28.16%. Intercropping also reduced the Cd contents in Z. acidojujuba seedlings, reduced the available Cd content and the catalase activity in soil. Intercropping with farmland ecotype S. photeinocarpum self-anvilgeneration significantly reduced the Cd content in roots, shoots part in Z. acidojujuba seedlings by 29.60%, and significantly reduced the available Cd content in soil by 16.25%. At the same time, intercropping increased the activity of soil urease and invertase activity. The self-anvilgeneration of farmland ecotype S. photeinocarpum significantly reduced the Cd content in roots, shoots part in Z. acidojujuba seedlings and significantly reduced the available Cd content in soil. Grafting increased the Cd enrichment ability of S. photeinocarpum, and self-anvilgeneration of S. photeinocarpum showed the better enrichment effect. Compared to the un-grafting generation, biomass in root and above ground part of self-anvilgeneration of farmland ecotype S. photeinocarpum increased by 55.84% and 49.23%, respectively; while Cd content increased by 31.68% and 45.27%, respectively, and Cd accumulation content increased by 69.77% and 72.18%, respectively. Therefore, under the condition of Cd contamination, intercropping the post-grafting generation of two ecotypes of S. photeinocarpum with Z. acidojujuba had a significant effect on remediation of cadmium, and the self-anvilgeneration of farmland ecotype S. photeinocarpum was the best.