The experiments of sugarcane combination evaluation with 119 combinations from 2017 to 2018 crossing season were conducted in Nanning, Chongzuo and Laibin of Guangxi province. The complex variance analysis and evaluation of genetic parameters in brix weight were took into account as well as the combination stability was analyzed by the regression analysis model and AMMI model. The results showed that differences of brix weight among combinations, environments and interaction between environments and combinations were both highly significant (P<0.01), and the broad-sense heritability of brix weight belonged to medium level or slightly lower in 3 sites. In both Chongzuo and Laibin, variation coefficients of brix weight were large, but that in Nanning was small. The combinations, 643, 404, 575, 972, 636, 144, YC95, 1470, 755, 409, 701, 832, YC37 and 579 performed high yield, high genetic stability and stronger adaptability. The result of comprehensive analysis in both brix weight and selection rate of combination showed that the combinations 449, YC127, 796, YC44, 533, 570, YC123, 391, 546, 403, YC90 and 252 performed high brix weight and high selection rate of combination in Nanning. The combinations 643, 212, YC61, 432, 903, YC95, YC44, 368, YC83, YC127, YC112, 701, 411, YC90 and YC123 demonstrated high brix weight and high selection rate of combination in Chongzuo. The combinations, 643, 404, 449, 144, 403 and YC48 had high brix weight and high selection rate of combination in Laibin.