To investigate the effects on growth, nutritive composition and the activities of digestive enzyme, nonspecific immunity enzyme of juvenile Sebastiscus marmoratus, we fed with soft pellet feed(group Ⅰ) and expanded pellet feed(group Ⅱ) for 8 weeks. The results showed, the group Ⅰ were in favor of the relative weight–growth rate and the feed conversion rate which were 145.67% and 1.77 in group Ⅰ and 110.73% and 1.67 in group Ⅱ; while the group Ⅱ had advantages on the protein efficiency ratio which was 119.41% in group Ⅰ and 130.90% in group Ⅱ. No significant difference between the two groups showed in fatness and survival rate. The moisture content and the crude fat content of group Ⅱ(75.68% and 2.37%) were significantly higher than those of group Ⅰ(75.41% and 2.05%), however, the crude ash content and the crude protein content showed a contrary tendency. The activities of pepsin, trypsin, lipase and amylase in liver and stomach of group Ⅱ were significantly higher than those of group Ⅰ, while trypsin activity in intestine of group Ⅰ was significantly higher than that of group Ⅱ, the activities of glutathione peroxidase, catalase and superoxide dismutase in liver of group Ⅱ were significantly higher than those of group Ⅰ. In conclusion, soft pellet feed might play a role in promoting the growth of juvenile Sebastiscus marmoratus, expanded pellet feed reduced the feed conversion rate, enhanced the efficiency of protein, and increased the activities of digestive enzyme and nonspecific immunity enzyme of juvenile Sebastiscus marmoratus. Both of them had effects on muscle nutrition.